Furin

Furin

furin, FES upstream region, dibasic processing enzyme, furin, membrane associated receptor protein, paired basic amino acid residue-cleaving.
FURIN (furin (paired basic amino acid cleaving enzyme)), Authors: Abdel-Majid Khatib, Fatma Sfaxi. Published in: Atlas Genet Cytogenet Oncol Haematol.
Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. Cao J, Rehemtulla A, Pavlaki M, Kozarekar P, Chiarelli C. Increased furin activity enhances the malignant phenotype of human head and neck cancer cells. Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino Furin site. Keywords summarise the content of a UniProtKB Furin and facilitate the search for proteins of. Wick W, Wild-Bode C, Frank B, Weller M.
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